publications

Research Articles

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Marina N, Christie IN, Korsak A, Doronin M, Brazhe A, Hosford PS, Wells JA, Sheikbahaei S, Humound I, Paton JFR, Lythgoe MF, Semyanov A, Kasparov S and Gourine AV. Astrocytes monitor cerebral perfusion and control systemic circulation to maintain brain blood flow. Nature Communications 2020

Hosford PS, Mosienko V, Kishi K, Jurisic G, Seuwen K, Kinzel B, Ludwig MG, Wells JA, Christie IN, Koolen L, Abdala AP, Liu BH, Gourine AV, Teschemacher AG, Kasparov S. CNS distribution, signalling properties and central effects of G-protein coupled receptor 4. Neuropharmacology 2018

Hosford PS, Christie IN, Niranjan A, Aziz Q, Anderson N, Ang R, Lythgoe MF, Wells JA, Tinker A, Gourine AV. A critical role for the ATP-sensitive potassium channel subunit KIR1 in the control of cerebral blood flow. JCBFM 2018

Marina N, Turovsky E, Christie IN, Hosford PS, Hadjihambi A, Korsak A, Ang R, Mastitskaya S, Sheikhbahaei S, Theparambil SM, Gourine AV. Brain metabolic sensing and metabolic signalling at the level of an astrocyte. Glia 2018

Christie IN, Wells JA, Kasparov S, Gourine AV, Lythgoe MF (2017) Volumetric Spatial Correlations of Neurovascular Coupling Studied using Single Pulse Opto-fMRI. Sci Rep. 7: 41583

Niranjan A, Christie IN, Solomon SG, Wells JA, Lythgoe MF (2016) fMRI mapping in the visual system in the mouse brain with interleaved snapshot GE-EPI. Neuroimage 139: 337-345

Angelova PR, Kasymov V, Christie I, Sheikhbahaei S, Turovsky E, Marin N, Korsak A, Zwicker J, Teschemacher AG, Ackland GL, Funk GD, Kasparov S, Abramov AY, Gourine AV (2015) Functional Oxygen Sensitivity of Astrocytes. J. Neurosci 35: 10460-73

Wells JA*, Christie IN*, Hosford PS, Huckstepp RT, Angelova PR, Vihko P, Cork SC, Abramov AY, Teschemacher AG, Kasparov S,Lythgoe MF, Gourine AV (2015) A critical role for purinergic signalling in the mechanisms underlying generation of BOLD fMRI responses. J. Neurosci, 35: 5284-92

Christie IN*, Wells JA*, Southern P, Marina N, Kasparov S, Gourine AV, Lythgoe MF. (2012) fMRI response to blue light delivery in the naïve brain: Implications for combined optogenetic fMRI studies. Neuroimage; 66C: 634-641

Hendry N, Christie I, Rabiner EA, Laruelle M, Watson J. (2011) In vitro assessment of the agonist properties of the novel 5-HT1A receptor ligand, CUMI-101 (MMP), in rat brain tissue. Nucl Med Biol; 38(2):273-7

Evans AK, Reinders N, Ashford KA, Christie IN, Wakerley JB, Lowry CA. (2008) Evidence for serotonin synthesis-dependent regulation of in vitro neuronal firing rates in the midbrain raphe complex. Eur J Pharmacol; 590 (1-3):136-49